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Immunologic causes of thrombocytopenia can be caused by certain medications, for example, sulfonamide antibiotics, carbamazepine (Tegretol, Tegretol XR , Equetro, Carbatrol), digoxin (Lanoxin), quinine (Quinerva, Quinite, QM-260), quinidine (Quinaglute, Quinidex), acetaminophen, and rifampin

If an oral pigmented lesion is not thickened, but is larger in diameter, has any variation in color, cannot be diagnosed as tattoo based on radiographic findings, or has irregular borders it should be excised

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Avoid putting the medication on ice or directly against the ice pack, which can freeze the medication